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Sinopharm Covid-19 vaccines appear safe, effective, says study

May 27, 2021 by admin Leave a Comment

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JAKARTA: Two vaccines made by China’s Sinopharm appear safe and effective against COVID-19, according to a study published in a medical journal.
Scientists had been waiting for more details about the two vaccines, even though they already are being used in many countries, and one recently won the backing of the World Health Organisation for emergency use.
The report, published online in the Journal of the American Medical Association, concluded the two vaccines are about 73 per cent and 78 per cent effective, as Sinopharm has previously claimed.
Researchers from Sinopharm and its local partners in the Middle East say the trial involved around 40,380 participants with the company’s two vaccines — one developed by the Wuhan Institute of Biological Products and the other by the Beijing Institute of Biological Products — and a placebo.
The trial was carried out in four countries — Bahrain, the United Arab Emirates, Egypt and Jordan. However, the study provided data for just Bahrain and the UAE.
“There’s nothing very surprising. It’s consistent with what they have claimed previously, but it does not completely eliminate the doubts about Sinopharm,” said Jin Dong-yan, a medical professor at the University of Hong Kong who was not involved with the study.
He raised doubts about how protective the vaccine was based on a recent surge of cases in the island nation of Seychelles, which had vaccinated a large majority of its population with the Sinopharm vaccine.
The study, performed mostly in younger men, had little information about the vaccine’s effectiveness against severe disease. Some experts also expressed concern at the shortage of female participants, with nearly 85 per cent being male.
“It’s important to make sure you have tested it in enough women to be able to start seeing any possible safety concerns,” said Ashley St. John, an associate professor at Duke-NUS Medical School in Singapore.
A spokesperson for the company did not immediately respond to a request for comment.
The vaccines, both of which are made with inactivated viruses, have already been given to millions of people across the world.
The World Health Organisation cleared the Beijing Institute of Biological Products’ shot for emergency use in early May, making it the first Chinese vaccine to receive the certification.
Chinese Foreign Minister Wang Yi said in April that China has provided vaccines to more than 100 countries, although it has not identified them. While China has six vaccines in use, the majority of its exports come from two companies: Sinopharm and Sinovac.



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Filed Under: Marketing Tagged With: Covid19, effective, safe, Sinopharm, study, vaccines

Young Covid survivors not safe from reinfection: Lancet

April 16, 2021 by admin Leave a Comment

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NEW YORK: If you are planning to avoid vaccination just because you are a Covid survivor, think twice. According to a new study, despite a prior Covid-19 infection young people can likely catch the virus again and may still transmit it to others.
Even after a previous infection and the presence of antibodies, vaccination is still necessary to boost immune responses, prevent reinfection, reduce transmission, and that young person should take up the vaccine wherever possible, asserts the study published in the journal The Lancet Respiratory Medicine.
“Immunity is not guaranteed by past infection, and vaccinations that provide additional protection are still needed for those who have had Covid-19,” said Professor Stuart Sealfon, from the Icahn School of Medicine at Mount Sinai, the US.
In the study, the team involved 2,346 young and fit Marines from the US Marine Corps – 189 were seropositive (they had previously been infected with SARS-CoV-2 and had antibodies) and 2,247 were seronegative at the start of the study.
Across both groups of recruits, there were 1,098 (45 percent) new infections between May and November 2020. Among the seropositive participants, 19 (10 percent) tested positive for a second infection during the study. Of the recruits who were seronegative, 1,079 (48 percent) became infected during the study.
Further, they found that, among the seropositive group, participants who became reinfected had lower antibody levels against the SARS-CoV-2 virus than those who did not become reinfected. The neutralizing antibodies were also less common – in 45 (83 percent) of 54 uninfected, and in six (32 percent) of 19 reinfected participants.
In addition, they found the viral load (the amount of measurable SARS-CoV-2 virus) in reinfected seropositive recruits was on average only 10 times lower than in infected seronegative participants, which could mean that some reinfected individuals could still have a capacity to transmit infection. However, this needs further investigation, the team said.

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Filed Under: Marketing Tagged With: Covid, Lancet, reinfection, safe, survivors, Young

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